P-OBS-JM-072 Obstetrical Clostridium Difficile Infection: A Retrospective Cohort Study

Clostridium difficile infection in children : A retrospective cohort study from a 38 pediatric hospital 39 40

Severe clinical outcome is uncommon in Clostridium difficile infection in children: a retrospective cohort study

BACKGROUND Clostridium difficile infection (CDI) is the most common cause of health care-associated diarrhea in children and adults. Although serious complications of CDI have been reported to be increasing in adults, this trend has not yet been demonstrated in children. The purpose of this study was to examine the features of CDI in a pediatric population, with special attention to the occurre...

Indeterminate tcdB using a Clostridium difficile PCR assay: a retrospective cohort study

BACKGROUND C. difficile (CD) real-time polymerase chain reaction (PCR) for toxin B gene (tcdB) is more sensitive, and reduces turnaround time when compared to toxin immunoassay. We noted typical amplification curves with high tcdB cycle thresholds (Ct) and low endpoints (Ept) that are labeled negative by the Xpert(®) C. difficile assay (Cepheid) and undertook this study to determine their signi...

Clostridium difficile in Inflammatory Bowel Disease: A Retrospective Study

Aim To investigate the epidemiology and risk factors of Clostridium difficile infections (CDI) in patients with inflammatory bowel disease (IBD). Methods This is a retrospective study of patients diagnosed with IBD. 1006 charts were screened and 654 patients met the inclusion criteria. Patients were divided into 2 cohorts based on the presence of prior diagnosis of CDI. Statistical analysis w...

Clostridium difficile Infection.

Clostridium difficile infection is a major health care challenge in terms of patient and economic consequences. For the patient, it is a morbid and sometimes a life-threatening iatrogenic complication of antibiotic treatment. In the United States, the provider's institution may face financial penalties, because the Centers for Disease Control and Prevention views this as an iatrogenic health ca...